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RELATED CATEGORIES
Bussey-Saksida Touch Systems > Chambers and Components for Mice
ABET II Interface and Software > ABET II Applications > Bussey Applications

TRIAL-UNIQUE NONMATCHING-TO-LOCATION TASK - TUNL - FOR MICE

Model 89545

Trial-unique Nonmatching-to-Location Task - TUNL - for Mice
 
   
 

DETAILS

TUNL can be thought of as a version of delayed nonmatching-to-place (DNMTP), in which the subjects are presented with a sample location and, following a delay, with the (incorrect, S-) sample location and a (correct, S+) nonmatching location. DNMTP has been shown to be vulnerable to non-spatial mediating strategies. TUNL eliminates these problems by using multiple, trial-unique locations, preventing the use of mediating strategies. Animals with lesions in the dorsal hippocampus or decreased hippocampal neurogenesis were impaired when the locations were close together, but not when they were far apart. This feature also renders the task exquisitely sensitive to hippocampal dysfunction, tapping both the role of the hippocampus in memory and in pattern separation.

Note: The mouse version of TUNL is the only Bussey-Saksida Application that has not produced a desired level of animal performance in mice comparable to the levels reached in rats.  We hope to improve this as on going investigations manipulate parameters and procedures that will eventually be incorporated into a validated product.  In the mean time, mouse TUNL is sold as is for interested labs.

ACCESSORIES

REQUIRED ACCESSORIES

Bussey-Saksida Mouse Touch Screen Chamber Package Image

Bussey-Saksida Mouse Touch Screen Chamber Package
Model 80614

Not just another square sheet metal box, the Bussey-Saksida chamber has a unique trapezoidal wall shape to focus the animal's attention and is made from machined parts that simply slot together. The chamber can also be configured to a modular square chamber with panels, levers, lights, and a range of other operators.

NEXT EVENT: Society for Neuroscience,  November 3 - 7, 2018     Details >>

CONTACT US

Lafayette Instrument Company
3700 Sagamore Pkwy N
Lafayette, IN 47904

Phone: (765) 423-1505
Fax: (765) 423-4111
info@lafayetteinstrument.com

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CONTACT US

Lafayette Instrument Company
3700 Sagamore Pkwy N
Lafayette, IN 47904

Phone: (765) 423-1505
Fax: (765) 423-4111

info@lafayetteinstrument.com

Copyright © 2009 - 2018 Lafayette Instrument Company. All Rights Reserved.