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Bussey-Saksida Touch Systems > Chambers and Components for Rats
For more information about the ever expanding amount of published research using our Touch Screen Systems, visit the DOWNLOADS and SCIENCE sections! For recent news about the system, check out our news page!
Look to Lafayette Instrument Company for a "Science above Hardware" approach not found from any other supplier. The fully validated chambers described below are supported by ready to run ABET II Touch Paradigms including images, and a Whisker ® Server-based Controller for up to four test chambers. Plus, we provide the ability for the user to write their own scheduling, with web-based training. ABET II Touch software gives you ease of use, programming power, data analysis, versatility, and flexibility.
Visit the DOWNLOADS tab for videos of these tasks.
VISUAL DISCRIMINATION AND REVERSAL TASK (VDR)
Age-related impairments in the R6/2 Huntington’s disease mouse model
Morton, Skillings, Bussey & Saksida (2006) Nature Methods
PAIRED ASSOCIATE LEARNING TASK (PAL)
Intra-hippocampal infusions of MK-801 impair performance of the PAL task
But perhaps the most promising data from this task comes from our studies using donepezil, an acetylcholinesterase inhibitor that is a commonly prescribed drug for AD in the UK. Donepezil enhanced performance on PAL in a dose-dependent manner. This result shows that PAL is able to detect cognitive enhancements, as well as impairments.
LOCATION DISCRIMINATION TASK (LD)
McTighe, Mar, Romberg, Bussey & Saksida (2009) NeuroReport
Neurogenesis knock-down impairs pattern separation in the Location Discrimination Task
Clelland, Choi, Romberg, Clemenson, Fragniere, Tyers, Jessberger, Saksida, Barker, Gage & Bussey (2009) Science
Dorsal hippocampal lesions impair pattern separation in the Location Discrimination Task
McTighe, Mar, Romberg, Bussey & Saksida (2009) NeuroReport
AUTOSHAPING
Impairments in Autoshaping (Pavlovian approach) following posttraining injections of the dopamine D1 antagonist SCH23390 or the NMDA antagonist AP-5.
Lecture Poster put together for Prof. Tim Bussey and the Distinguished Lecture Series located at Seoul National University on September 21, 2011.
Prof. Tim Bussey's profile at the University of Cambridge.
Guardian article on recent research indicating why regular exercise benefits brain cell growth.
BBC Article on recent research indicating why regular exercise benefits memory.
BBC Article on recent research indicating why regular exercise benefits brain power. Based on a Cambridge University study.
Abstract and graph presented at British Association for Psychopharmacology (BAP) 2010.
Featured application plans to use touch screens with microdialysis for sampling in the extracellular space. As shown in the image our design enables the lines to the animals to be as short as possible (the entry point to the chamber are at the side at the connection panel with the cooling fan) and the carousel can be rolled in and out on a shelf.
Bussey-Saksida Touch Screen Chambers for Rodents
CamTouch Technical Standard
Touch Screen System Cleaning Tips
Rodent Touchscreen Bibliography
Neurosciences CEDD's Study of Effects of Compound X in a two stimulus discrimination and reversal learning task using novel touchscreen apparatus
Prof. Bussey's Profile
Start running and watch your brain grow, say scientists:
Physical exercise helps brains grow, mouse study finds:
Running could help jog memory and help brain grow, says Cambridge study:
Pairwise discrimination followed by reversal in C57BL6/J using mouse touchscreen operant boxes.
Whisker: A client–server high-performance multimedia research control system
New translational assays for preclinical modelling of cognition in schizophrenia: The touchscreen testing method for mice and rats
The Drug Deadlock
Bussey Rodent Touch Screen Biography List
Stress facilitates late reversal learning using a touchscreen-based visual discrimination procedure in male Long Evans rats
Post-training depletions of basolateral amygdala serotonin fail to disrupt discrimination, retention, or reversal learning
Distinct patterns of outcome valuation and amygdala-prefrontal cortex synaptic remodeling in adolescence and adulthood
Comparison of the validity of the use of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder in males and females
Rat Touch Screen TUNL Video
Rat Touch Screen TUNL Video 2
Long Rat Touch Screen TUNL Video
Touchscreen-Based Cognitive Tasks Reveal Age-Related Impairment in a Primate Aging Model, the Grey Mouse Lemur (Microcebus murinus) - Video
Tree Shrew Close Up 3
Tree Shrew Monitoring 3