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BUSSEY-SAKSIDA MOUSE TOUCH SCREEN CHAMBER PACKAGE
Model 80614

Bussey-Saksida Mouse Touch Screen Chamber Package

DESCRIPTION

For more information about the ever expanding amount of published research using our Touch Screen Systems, visit the DOWNLOADS and SCIENCE sections! For more news about the system, check out our news page!

Look to Lafayette Instrument Company for a "Science above Hardware" approach not found from any other supplier. The fully validated chambers described below are supported by ready to run ABET II Touch Paradigms including images, and a Whisker ® Server-based Controller for up to four test chambers. Plus, we provide the ability for the user to write their own scheduling, with web-based training. ABET II Touch software gives you ease of use, programming power, data analysis, versatility, and flexibility.

Disassembled Touch Screen System

TOUCH SCREEN PARADIGMS

Visit DOWNLOADS for videos of these tasks.

VISUAL DISCRIMINATION AND REVERSAL TASK (VDR)
Age-related impairments in the R6/2 Huntington's disease mouse model

 
Morton, Skillings, Bussey & Saksida (2006) Nature Methods

PAIRED ASSOCIATE LEARNING TASK (PAL)
Intra-hippocampal infusions of MK-801 impair performance of the PAL task

But perhaps the most promising data from this task comes from our studies using donepezil, an acetylcholinesterase inhibitor that is a commonly prescribed drug for AD in the UK.  Donepezil enhanced performance on PAL in a dose-dependent manner. This result shows that PAL is able to detect cognitive enhancements, as well as impairments.

LOCATION DISCRIMINATION TASK (LD)


McTighe, Mar, Romberg, Bussey & Saksida (2009) NeuroReport

Neurogenesis knock-down impairs pattern separation in the Location Discrimination Task


Clelland, Choi, Romberg, Clemenson, Fragniere, Tyers, Jessberger,  Saksida, Barker, Gage & Bussey (2009) Science

Dorsal hippocampal lesions impair pattern separation in the Location Discrimination Task


McTighe, Mar, Romberg, Bussey & Saksida (2009) NeuroReport

AUTOSHAPING

Data from C57/Bl6 mice on the Autoshaping task. A stimulus (white rectangle) is shown on either the left or right of the screen for (usually) 10 seconds. Over trials the animal learns that the CS+ predicts reward and makes increasingly more responses to the CS+, and fewer responses to the CS-.

INCLUDES

 

SPECIFICATIONS

ANIMAL WORKING AREA

SOUND ATTENUATION CUBICLE (SAC)

 

FEATURES

Chamber shown with modular panel walls (Model 80614-3) and corresponding reward trough (Model 80614-17)
Chamber shown with modular panel walls (Model 80614-3)
and corresponding reward trough (Model 80614-17).

 

SCIENCE

LECTURE POSTER

Lecture Poster put together for Prof. Tim Bussey and the Distinguished Lecture Series located at Seoul National University on September 21, 2011.

PROFILE OF PROF. TIM BUSSEY

Prof. Tim Bussey's profile at the University of Cambridge.

TOUCHSCREENS AT WESTERN UNIVERSITY

Details on the usage of Bussey-Saksida Touchscreen Chambers at Western University.

TOUCHSCREEN TESTING AT UNIVERSITY OF CAMBRIDGE

Improving cognitive testing on animals to treat human disorders: Technology developed at the University of Cambridge is transforming the way cognitive tests are performed on animals, leading to more directed experiments and ultimately aiding development of new drugs to treat schizophrenia and other neurocognitive disorders.

START RUNNING AND WATCH YOUR BRAIN GROW, SAY SCIENTISTS

Guardian article on recent research indicating why regular exercise benefits brain cell growth.

PHYSICAL EXERCISE HELPS BRAINS GROWN, MOUSE STUDY FINDS

BBC Article on recent research indicating why regular exercise benefits memory.

RUNNING COULD HELP JOG MEMORY AND HELP BRAIN GROW, SAYS CAMBRIDGE STUDY

BBC Article on recent research indicating why regular exercise benefits brain power. Based on a Cambridge University study.

PAIRWISE DISCRIMINATION FOLLOWED BY REVERSAL IN C57BL6/J USING MOUSE TOUCH SCREEN OPERANT BOXES

Abstract and graph presented at British Association for Psychopharmacology (BAP) 2010.

CUSTOM SYSTEM INTEGRATIONS AVAILABLE ON REQUEST

Featured application plans to use touch screens with microdialysis for sampling in the extracellular space. As shown in the image our design enables the lines to the animals to be as short as possible (the entry point to the chamber are at the side at the connection panel with the cooling fan) and the carousel can be rolled in and out on a shelf.

 

OPTIONAL ACCESSORIES

ABET II SOFTWARE FOR TOUCH SCREENS
Model 89505
Operant monitoring and control software for use with the Touch Screen modular hardware.
PERISTALTIC PUMP FOR LIQUID REWARD FOR MICE
Model 80204M
Single channel peristaltic pump featuring electronic control of the pump head including an electronic brake, to ensure accurate delivery of liquid reward down to a minimum of 7 microlitres. Volume is calibrateable when used with Whisker and ABET II software.
PELLET DISPENSER WITH 20MG INTERCHANGABLE PELLET AND OPTIONAL STAND
Model 80209-20
A reliable pellet dispenser that features powerful motor drive with optical stops and optional pellet drop detection. Also available with an optional vertical or cantilever stand.
TWO-CHOICE VISUAL DISCRIMINATION REVERSAL FOR MICE
Model 89540
The task involves learning that one of two shapes displayed simultaneously on the screen is correct. Touching the correct stimuli will be rewarded by delivery of food to the reward tray.
PAIRED-ASSOCIATE LEARNING TASK - PAL - FOR MICE
Model 89541
In humans this task has proved to be highly effective for the early detection of Alzheimer’s disease. In the PAL task for rodents, rats learn and remember which of three objects goes in which of three spatial locations.
VISUOMOTOR CONDITIONAL LEARNING - VMCL - FOR MICE
Model 89542
This is a habit or stimulus-response task in which the rodent learns a rule of the type If shape A presented, respond to the left location; if shape B is presented, respond to the right location.
5-CHOICE SERIAL REACTION TIME TASK - 5CSRT - FOR MICE
Model 89543
This task requires the rodent to respond to a brief visual stimulus presented randomly in one of 5 locations. This task in rodents is sensitive to cortical manipulations, especially those involving prefrontal cortex, and is highly dependent on cholinergic transmission.
TRIAL-UNIQUE NONMATCHING-TO-LOCATION TASK - TUNL - FOR MICE
Model 89545
TUNL can be thought of as a version of delayed nonmatching-to-place, usually carried out in a conventional Skinner box with levers, in which the rats are presented with a sample location and, following a delay, are presented with two choice locations.
LOCATION DISCRIMINATION - LD - FOR MICE
Model 89546
The rodents are required to discriminate between two white squares on the screen. Responses to squares on one side of the screen will be rewarded, while responses on the other side of the screen will be punished with a time out period.
AUTOSHAPING FOR MICE
Model 89544
The task measures a Pavlovian response to the screen. This is a very rapidly administered test of simple classical conditioning that is dependent on a reward system centred on the ventral striatum.
 

CONTACT US

Lafayette Instrument Company
PO Box 5729
Lafayette, IN 47903

Phone: (765) 423-1505
Fax: (765) 423-4111

info@lafayetteinstrument.com

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